pentobarbital will decrease the level or effect of pimavanserin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Bildskärm. Avoid coadministration if possible. Skärm for reduced pimavanserin efficacy. An increase in pimavanserin dosage may vädja needed.pentobarbital will decrease the level or effect of budesonide ort affecti